PUBLICATIONS
pre-print
BIORXIV
John W. Hickey, Winston R. Becker, Stephanie A. Nevins, Aaron Horning, Almudena Espin Perez, Roxanne Chiu, Derek C. Chen, Daniel Cotter, Edward D. Esplin, Annika K. Weimer, Chiara Caraccio, Vishal Venkataraaman, Christian M. Schürch, Sarah Black, Maria Brbić, Kaidi Cao, Jure Leskovec, Zhengyan Zhang, Shin Lin, Teri Longacre, Sylvia K. Plevitis, Yiing Lin, Garry P. Nolan, William J. Greenleaf, Michael Snyder
pre-print
BIORXIV
Yu Xin Wang, Colin Holbrook, James N. Hamilton, Jasmin Garoussian, Mohsen Afshar, Shiqi Su, Christian M. Schürch, Michael Y. Lee, Yury Goltsev, Anshul Kundaje, Garry P. Nolan, Helen M. Blau
pre-print
RESEARCH SQUARE
A tissue atlas of ulcerative colitis to guide TNF inhibitor therapy
Aaron Mayer, Derek Holman, Utkarsh Tandon, Salil Bhate, Sunil Bodapati, Graham Barlow, Jeff Chang, Sarah Black, Erica Crenshaw, Brigid Boland, Sarah Streett, William Sandborn, John Chang, Sanjiv Gambhir, Garry Nolan, Christian Schürch#, Stephan Rogalla#
10/2022
CANCER CELL INTERNATIONAL
Simon Heumos, Sandra Dehn, Konstantin Bräutigam, Marius C. Codrea, Christian M. Schürch, Ulrich M. Lauer, Sven Nahnsen, Michael Schindler
09/2022
LEUKEMIA
Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance
Elias D. Bührer, Michael A. Amrein, Stefan Forster, Stephan Isringhausen, Christian M. Schürch, Salil S. Bhate, Tess Brodie, Joel Zindel, Deborah Stroka, Mohamad Al Sayed, César Nombela-Arrieta, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
09/2022
SCIENCE TRANSLATIONAL MEDICINE
Giovanny J. Martínez-Colón, Kalani Ratnasiri, Heping Chen, Sizun Jiang, Elizabeth Zanley, Arjun Rustagi, Renu Verma, Han Chen, Jason R. Andrews, Kirsten D. Mertz, Alexandar Tzankov, Dan Azagury, Jack Boyd, Garry P. Nolan, Christian M. Schürch, Matthias S. Matter, Catherine A. Blish, Tracey L. McLaughlin
07/2022
BRAIN
Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV
Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M. Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler
07/2022
SCIENCE ADVANCES
Tala Shekarian, Carl P. Zinner, Ewelina M. Bartoszek, Wandrille Duchemin, Anna T. Wachnowicz, Sabrina Hogan, Manina M. Etter, Julia Flammer, Chiara Paganetti, Tomás A. Martins, Philip Schmassmann, Steven Zanganeh, Francois Le Goff, Manuele G. Muraro, Marie-Françoise Ritz, Darci Phillips, Salil S. Bhate, Graham L. Barlow, Garry P. Nolan, Christian M. Schürch#, Gregor Hutter#
02/2022
CELL SYSTEMS
Tissue Schematics map the specialization of immune tissue motifs and their appropriation by tumors
Salil S. Bhate, Graham L. Barlow, , Garry P. Nolan
01/2022
BMC BIOINFORMATICS
Michael Y. Lee, Jacob S. Bedia, Salil S. Bhate, Graham L. Barlow, Darci J. Phillips, Wendy J. Fantl, Garry P. Nolan, Christian M. Schürch
01/2022
RESPIRATION
Konstantin Bräutigam, Stefan Reinhard, José A. Galván, Martin Wartenberg, Ekkehard Hewer, Christian M. Schürch
12/2021
FRONT IMMUNOL
Sizun Jiang, Nilanjan Mukherjee, Richard S. Bennett, Han Chen, James Logue, Bonnie Dighero-Kemp, Jonathan R. Kurtz, Ricky Adams, Darci Phillips, Christian M. Schürch, Yury Goltsev, John Hickey, Erin Francis McCaffrey, Alea Delmastro, Pauline Chu, Rachel Reader, Rebekah I. Keesler, Jose A. Galván, Inti Zlobec, Koen K. A. Van Rompay, David X. Liu, Lisa E. Hensley, Garry P. Nolan, David R. McIlwain
11/2021
CANCERS
Johannes Graf, Stefan Forster, Frido Bruehl, Yara Banz, Mahmoud Hallal, Justine Brodard, Vera Ulrike Bacher, Ramanjaneyulu Allam, Christian M. Schürch, Nicolas Bonadies
11/2021
CELL HOST & MICROBE
Human influenza virus challenge identifies cellular correlates of protection for oral vaccination
David R. McIlwain, Han Chen, Zainab Rahil, Neda Hajiakhoond Bidoki, Sizun Jiang, Zach Bjornson, Nikita S. Kolhatkar, C. Josefina Martinez, Brice Gaudillière, Julien Hedou, Nilanjan Mukherjee, Christian M. Schürch, Angelica Trejo, Melton Affrime, Bonnie Bock, Kenneth Kim, David Liebowitz, Nima Aghaeepour, Sean N. Tucker, Garry P. Nolan
11/2021
CANCER IMMUNOLOGY RESEARCH
Supporting the next generation of scientists to lead cancer immunology research
Elise Alspach*, Ryan D. Chow*, Shadmehr Demehri*, Jennifer Guerriero*, Shashi Gujar*, Nir Hacohen*, Felix Hartmann*, Beth Helmink*, William H. Hudson*, Won Jin Ho*, Leyuan Ma*, Barbara Maier*, Vivien Maltez*, Brian Miller*, Noor Momin*, Amy Moran* Erin Parry*, Padmini S. Pillai*, Sarwish Rafiq*, Miguel Reina Campos*, Pam Rosato*, Nils-Petter Rudqvist*, Megan K. Ruhland*, Idit Sagiv-Barfi*, Avinash Sahu*, Robert Samstein*, Christian M. Schürch*, Debattama R. Sen*, Daniela Thommen*, Yochai Wolf*, Roberta Zappasodi*
11/2021
CANCERS
Magdalena M. Brune, Achim Rau, Mathis Overkamp, Tim Flaadt, Christian M. Schürch, Birgit Federmann, Stefan Dirnhofer, Falko Fend, Alexandar Tzankov
11/2021
NATURE COMMUNICATIONS
Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma
Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch#, Garry P. Nolan#
10 / 2021
CELL REPORTS MEDICINE
Tsuguhisa Nakayama, Ivan T. Lee, Sizun Jiang, Matthias S. Matter, Carol H. Yan, Jonathan B. Overdevest, Yury Goltsev, Liang-Chun Shih, Chun-Kang Liao, Chien-Ting Wu , Bokai Zhu, David Zarabanda, Angela Yang, Christian M. Schürch, Pauline Chu, Han Chen, David R. McIlwain, Nicole A. Borchard, Phil A. Gall, Sachi S. Dholakia, Le Xu, Anna K. Stalder, Peter Lidsky, Peter K. Jackson, Chih-Jaan Tai, Te-Huei Yeh, Raul Andino, Jason M. Duran, Kirsten D. Mertz , Zara M. Patel, Jasmin D. Haslbauer, Thomas Menter, Peter D. Canoll, Adam S. DeConde, Peter H. Hwang, Alexandar Tzankov, Garry P. Nolan, Jayakar V. Nayak
10/2021
DER RADIOLOGE
Mutiple myeloma from the pathologist's perspective
Antonio Vogelsberg, Christian M. Schürch, Falko Fend
07/2021
NATURE PROTOCOLS
CODEX multiplexed tissue imaging with DNA-conjugated antibodies
Sarah Black, Darci Phillips, John W. Hickey, Julia Kennedy-Darling, Vishal G. Venkataraaman, Nikolay Samusik, Yury Goltsev, Christian M. Schürch#, Garry P. Nolan#
07 / 2021
CELL REPORTS MEDICINE
Virtual and Augmented Reality for Biomedical Applications
Mythreye Venkatesan, Harini Mohan, Justin Ryan, Christian M. Schürch, Garry P. Nolan, David H. Frakes, Ahmet F. Coskun
05 / 2021
FRONT IMMUNOL
Darci Phillips, Christian M. Schürch, Michael S. Khodadoust, Youn H. Kim, Garry Nolan and Sizun Jiang
04 / 2021
FRONT PHARMACOL
Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer
Paulius Ruzgys, Stephan Böhringer, Ayse Sila Dokumaci, Yvonne Hari, Christian M. Schürch, Frido Brühl, Stefan Schürch, Sönke Szidat, Carsten Riether, Saulius Šatkauskas, Thomas Geiser, David Hradetzky, Amiq Gazdhar
03 / 2021
EUR J IMMUNOL
Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction
Julia Kennedy-Darling, Salil S. Bhate, John W. Hickey, Sarah Black, Graham L. Barlow, Gustavo Vazquez, Vishal G. Venkataraaman, Nikolay Samusik, Yury Goltsev, Christian M. Schürch#, Garry P. Nolan#
03 / 2021
BLOOD
Diversity, localization and (patho)physiology of mature lymphocyte populations in the bone marrow
Christian M. Schürch, Chiara Caraccio, Martijn A Nolte
02 / 2021
NAT COMMUN
Nanoscopic subcellular imaging enabled by ion beam tomography
Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan
01 / 2021
CELL REPORTS
Carsten Riether, Ramin Radpour, Nils M. Kallen, Damian T. Bürgin, Chantal Bachmann, Christian M. Schürch, Ursina Lüthi, Miroslav Arambasic, Sven Hoppe, Christoph E. Albers, Gabriela M. Baerlocher, Adrian F. Ochsenbein
12 / 2020
SCIENCE
Inhibition of prostaglandin degrading enzyme 15-PGDH restores muscle strength in aged mice
Adelaida R. Palla, Meenakshi Ravichandran, Yu Xin Wang, Ludmila Alexandrova, Ann V. Yang, Peggy Kraft, Colin A. Holbrook, Christian M. Schürch, Andrew T. V. Ho, Helen M. Blau
10 / 2020
NAT COMMUN
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
Ivan T. Lee, Tsuguhisa Nakayama, Chien-Ting Wu, Yury Goltsev, Sizun Jiang, Phillip A. Gall, Chun-Kang Liao, Liang-Chun Shih, Christian M. Schürch, David R. McIlwain, Pauline Chu, Nicole A. Borchard, David Zarabanda, Sachi S. Dholakia, Angela Yang, Dayoung Kim, Han Chen, Tomoharu Kanie, Chia-Der Lin, Ming-Hsui Tsai, Katie M. Phillips, Raymond Kim, Jonathan B. Overdevest, Matthew A. Tyler, Carol H. Yan, Chih-Feng Lin, Yi-Tsen Lin, Da-Tian Bau, Gregory J. Tsay, Zara M. Patel, Yung-An Tsou, Alexandar Tzankov, Matthias S. Matter, Chih-Jaan Tai, Te-Huei Yeh, Peter H. Hwang, Garry P. Nolan, Jayakar V. Nayak, Peter K. Jackson
10 / 2020
J CLIN INVEST
Landscape of coordinated immune responses to H1N1 challenge in humans
Zainab Rahil, Rebecca Leylek*, Christian M. Schürch*, Han Chen*, Zach Bjornson, Shannon Christensen, Pier Federico Gherardini, Salil S. Bhate, Matthew H. Spitzer, Gabriela K. Fragiadakis, Nilanjan Mukherjee, Nelson Kim, Jennifer Yo, Melton Affrime, Bonnie Bock, Scott Hensley, Juliana Idoyaga, Nima Aghaeepour, Kenneth Kim, Garry P. Nolan, David R. McIlwain
09 / 2020
RESPIRATORY RESEARCH
Magdalena Matusiak, Christian M. Schürch
08 / 2020
CELL
Christian M. Schürch*#, Salil S. Bhate*, Graham L. Barlow*, Darci J. Phillips*, Luca Noti, Inti Zlobec, Pauline Chu, Sarah Black, Janos Demeter, David R. McIlwain, Nikolay Samusik, Yury Goltsev, Garry P. Nolan#
07 / 2020
CELL METABOLISM
Maria L. Balmer, Raja Epple, Eric H. Ma, Adrian Egli, Lukas Bubendorf, Katharina Rentsch, Anne-Kathrin Woischnig, Nina Khanna, Jonas Lötscher, Philippe Dehio, Gaëlle Perrin, Jan Warncke, Olivier P. Schären, Christian M. Schürch, Gunhild Unterstab, Andrew Thompson, Siegfried Hapfelmeier, Russell G. Jones, Christoph Hess
06 / 2020
J NUCLEAR MEDICINE
PET imaging of the natural killer cell activation receptor NKp30
Travis M. Shaffer, Amin Aalipour, Christian M. Schürch, Sanjiv S. Gambhir
04 / 2020
FRONT IMMUNOL
Chiara Caraccio , Sachi Krishna, Darci J. Phillips and Christian M. Schürch
04 / 2020
NAT COMMUN
Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity
Simona Pfister, Olivier P. Schären, Miguelangel Cuenca, Stefanie Hagemann, Stefanie S. Uster, Miguel A. Terrazos, Christian M. Schürch, Fernanda M. Coelho, Emma Slack, Maria L. Balmer, Siegfried Hapfelmeier
04 / 2020
NAT COMMUN
TNIK signaling imprints CD8+ T cell memory formation early after priming
Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Ursina Lüthi, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
03 / 2020
BMC IMMUNOLOGY
Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes
Han Chen, Christian M. Schürch, Kevin Noble, Kenneth Kim, Peter Krutzik, Erika O’Donnell, Jason Vander Tuig, Garry P. Nolan, David R. McIlwain
12/2019
VIRCHOWS ARCHIV
Christian M. Schürch, Leo Rasche, Leonie Frauenfeld, Niels Weinhold, Falko Fend
11/2019
PATHOL RES PRACT
Nora Schaumann, Mieke Raap, Laura Hinze, Luisa Rieger, Christian M. Schürch, Wiebke Antonopoulos, Stefanie Avril, Till Krech, Maximilian Dämmrich, Gian Kayser, Florian Puls, Florian Länger, Marianne Tinguely, Hans Kreipe, Matthias Christgen
10/2019
NATURE
07/2019
THYROID
Targeting CD47 in anaplastic thyroid carcinoma enhances tumor phagocytosis by macrophages and is a promising therapeutic strategy
Christian M. Schürch#, Matthias A. Roelli, Stefan Forster, Marie-Hélène Wasmer, Frido Brühl, Renaud S. Maire, Sergio Di Pancrazio, Marc-David Ruepp, Roland Giger, Anja M. Schmitt, Philippe Krebs, Roch-Philippe Charles, Matthias S. Dettmer#
05 / 2019
CELL
A multiscale map of the stem cell state in pancreatic adenocarcinoma
Nikki K. Lytle, L. Paige Ferguson, Nirakar Rajbhandari, Kathryn Gilroy, Raymond G. Fox, Anagha Deshpande, Christian M. Schürch, Michael Hamilton, Neil Robertson, Wei Lin, Pawan Noel, Martin Wartenberg, Inti Zlobec, Micha Eichmann, José A. Galván, Eva Karamitopoulou, Tami Gilderman, Lourdes Adriana Esparza, Yutaka Shima, Philipp Spahn, Randall French, Nathan E. Lewis, Kathleen M. Fisch, Roman Sasik, Sara Brin Rosenthal, Marcie Kritzik, Daniel Von Hoff, Haiyong Han, Trey Ideker, Aniruddha L. Deshpande, Andrew M. Lowy, Peter D. Adams, Tannishtha Reya
05/2019
GENES & IMMUNITY
CARving up colorectal cancer organoids in vitro
Christian M. Schürch
05 / 2018
FRONT ONCOL
Therapeutic antibodies for myeloid neoplasms – current developments and future directions
Christian M. Schürch
09 / 2017
ONCOIMMUNOLOGY
Christian M. Schürch#, Stefan Forster, Frido Brühl, Sara H. Yang, Emanuela Felley-Bosco, Ekkehard Hewer#
07 / 2017
PATHOBIOLOGY
Tumor heterogeneity in lymphomas – a different breed
Christian M. Schürch, Birgit Federmann, Leticia Quintanilla-Martinez, Falko Fend
06 / 2017
PLOS PATHOGENS
Stefanie Buschor, Miguelangel Cuenca, Stephanie S. Uster, Olivier P. Schären, Maria L. Balmer, Miguel A. Terrazos, Christian M. Schürch, Siegfried Hapfelmeier
05 / 2017
MOL CANCER THER
Maximilien Murone, Ramin Radpour, Antoine Attinger, Anne Vaslin Chessex, Anne-Laure Huguenin, Christian M. Schürch, Yara Banz, Saumitra Sengupta, Michel Aguet, Stefania Rigotti, Yogeshwar Bachhav, Frederic Massiere, Murali Ramachandra, Andres McAllister, Carsten Riether
02 / 2017
J EXP MED
Carsten Riether*, Christian M. Schürch*, Elias D. Bührer, Magdalena Hinterbrandner, Anne-Laure Huguenin, Sabine Hoepner, Inti Zlobec, Thomas Pabst, Ramin Radpour, Adrian F. Ochsenbein
12 / 2016
FRONT CELL INFECT MICROBIOL
Nicolas Studer, Lyne Desharnias, Markus Beutler, Sandrine Brugiroux, Miguel Terrazos, Laure Menin, Christian M. Schürch, Kathy D. McCoy, Sarah Kuehne, Nigel Minton, Bärbel Stecher, Rizlan Bernier-Latmani, Siegfried Hapfelmeier
07 / 2015
SCIENCE TRANSL MED
Carsten Riether*, Christian M. Schürch*, Christoph Flury, Magdalena Hinterbrandner, Linda Drück, Anne-Laure Huguenin, Gabriela M. Baerlocher, Ramin Radpour, Adrian F. Ochsenbein
07 / 2015
J CLIN INVEST
IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms
Lukas Mager, Carsten Riether*, Christian M. Schürch*, Yara Banz*, Marie-Hélène Wasmer, Regula Stuber, Alexandre P. Theocharides, Xiaohong Li, Yu Xia, Hirohisa Saito, Susumu Nakae, Gabriela M. Baerlocher, Kathy D. McCoy, Andrew J. Macpherson, Adrian F. Ochsenbein, Bruce Beutler, Philippe Krebs
07 / 2015
CELL DEATH DIFFER
Regulation of hematopoietic and leukemic stem cells by the immune system
Carsten Riether*, Christian M. Schürch*, Adrian F. Ochsenbein
04 / 2015
LEUK RES
CD47 protein expression in acute myeloid leukemia: a tissue microarray-based analysis
Serena Galli, Inti Zlobec, Christian Schürch, Aurel Perren, Adrian Ochsenbein, Yara Banz
03 / 2015
LEUKEMIA
Carsten Riether, Thomas Gschwend, Anne-Laure Huguenin, Christian M. Schürch, Adrian F. Ochsenbein
10 / 2014
J IMMUNOL
Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling
Maria Luisa Balmer, Christian M. Schürch, Yasuyuki Saito, Markus B. Geuking, Hai Li, Miguelangel Cuenca, Larisa V. Kovtonyuk, Kathy D. McCoy, Siegfried Hapfelmeier, Adrian F. Ochsenbein, Markus G. Manz, Emma Slack, Andrew J. Macpherson
04 / 2014
CELL STEM CELL
Christian M. Schürch*, Carsten Riether*, Adrian F. Ochsenbein
01 / 2014
PLOS PATHOGENS
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance
Benjamin Weber, Steffen Schuster, Daniel Zysset, Silvia Rihs, Nina Dickgreber, Christian Schürch, Carsten Riether, Mark Siegrist, Christoph Schneider, Helga Pawelski, Ursina Gurzeler, Pascal Ziltener, Vera Genitsch, Fabienne Tacchini-Cottier, Adrian Ochsenbein, Willy Hofstetter, Manfred Kopf, Thomas Kaufmann, Anette Oxenius, Walter Reith, Leslie Saurer, Christoph Mueller
12 / 2013
FRONT IMMUNOL
Dendritic cell-based immunotherapy for myeloid leukemias
Christian M. Schürch*, Carsten Riether*, Adrian F. Ochsenbein
04 / 2013
ONCOIMMUNOLOGY
Interferons in hematopoiesis and leukemia
Christian M. Schürch*, Carsten Riether*, Adrian F. Ochsenbein*
03 / 2013
PATHOL RES PRACT
Christian Schürch, Michèle Birrer, Isabelle Estella, Andreas Kappeler, Ekkehard Hewer, Istvan Vajtai
02 / 2013
J EXP MED
Christian M. Schürch*, Carsten Riether*, Michael A. Amrein, Adrian F. Ochsenbein
01 / 2013
SWISS MED WKLY
From “magic bullets” to specific cancer immunotherapy
Carsten Riether*, Christian Schürch*, Adrian F. Ochsenbein*
12 / 2012
ONCOIMMUNOLOGY
Modulating CD27 signaling to treat cancer
Carsten Riether*, Christian Schürch*, Adrian F. Ochsenbein*
07 / 2012
CANCER RES
CD27-signaling increases the frequency of regulatory T cells and promotes tumor growth
Christina Claus*, Carsten Riether*, Christian Schürch*, Matthias S. Matter, Tamara Hilmenyuk, Adrian F. Ochsenbein
02 / 2012
J CLIN INVEST
Christian Schürch*, Carsten Riether*, Matthias S. Matter, Alexandar Tzankov, Adrian F. Ochsenbein
09 / 2011
PLOS ONE
Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells
Matthias S. Matter, Tamara Hilmenyuk, Christina Claus, Romina Marone, Christian Schürch, Marianne Tinguely, Luigi Terracciano, Sanjiv A. Luther, Adrian F. Ochsenbein
07 / 2010
EUR J IMMUNOL
Chronic myelogenous leukemia maintains leukemia-specific CD8+ T cells through IL-7 signaling
Sabine Mumprecht*, Christian Schürch*, Sandro Scherrer, Christina Claus, Adrian F. Ochsenbein
08 / 2009
BLOOD
Sabine Mumprecht, Christian Schürch, Jürg Schwaller, Max Solenthaler, Adrian F. Ochsenbein
05 / 2009
BLOOD
Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells
Sabine Mumprecht, Christina Claus, Christian Schürch, Viktor Pavelic, Matthias S. Matter, Adrian F. Ochsenbein
03 / 2007
ANTIMICROB AGENTS CHEMOTHER
Denis Grandgirard, Christian Schürch, Philippe Cottagnoud, Stephen L. Leib