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BIORXIV

High Resolution Single Cell Maps Reveals Distinct Cell Organization and Function Across Different Regions of the Human Intestine

John W. Hickey, Winston R. Becker, Stephanie A. Nevins, Aaron Horning, Almudena Espin Perez, Roxanne Chiu, Derek C. Chen, Daniel Cotter, Edward D. Esplin, Annika K. Weimer, Chiara Caraccio, Vishal Venkataraaman, Christian M. Schürch, Sarah Black, Maria Brbić, Kaidi Cao, Jure Leskovec, Zhengyan Zhang, Shin Lin, Teri Longacre, Sylvia K. Plevitis, Yiing Lin, Garry P. Nolan, William J. Greenleaf, Michael Snyder

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BIORXIV

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Yu Xin Wang, Colin Holbrook, James N. Hamilton, Jasmin Garoussian, Mohsen Afshar, Shiqi Su, Christian M. Schürch, Michael Y. Lee, Yury Goltsev, Anshul Kundaje, Garry P. Nolan, Helen M. Blau

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RESEARCH SQUARE

A tissue atlas of ulcerative colitis to guide TNF inhibitor therapy

Aaron Mayer, Derek Holman, Utkarsh Tandon, Salil Bhate, Sunil Bodapati, Graham Barlow, Jeff Chang, Sarah Black, Erica Crenshaw, Brigid Boland, Sarah Streett, William Sandborn, John Chang, Sanjiv Gambhir, Garry Nolan, Christian Schürch#, Stephan Rogalla#

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10/2022

CANCER CELL INTERNATIONAL

Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Simon Heumos, Sandra Dehn, Konstantin Bräutigam, Marius C. Codrea, Christian M. Schürch, Ulrich M. Lauer, Sven Nahnsen, Michael Schindler

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09/2022

LEUKEMIA

Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance

Elias D. Bührer, Michael A. Amrein, Stefan Forster, Stephan Isringhausen, Christian M. Schürch, Salil S. Bhate, Tess Brodie, Joel Zindel, Deborah Stroka, Mohamad Al Sayed, César Nombela-Arrieta, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein

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09/2022

SCIENCE TRANSLATIONAL MEDICINE

SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages

Giovanny J. Martínez-Colón, Kalani Ratnasiri, Heping Chen, Sizun Jiang, Elizabeth Zanley, Arjun Rustagi, Renu Verma, Han Chen, Jason R. Andrews, Kirsten D. Mertz, Alexandar Tzankov, Dan Azagury, Jack Boyd, Garry P. Nolan, Christian M. Schürch, Matthias S. Matter, Catherine A. Blish, Tracey L. McLaughlin

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07/2022

BRAIN

Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV

Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M. Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler

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07/2022

SCIENCE ADVANCES

Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery

Tala Shekarian, Carl P. Zinner, Ewelina M. Bartoszek, Wandrille Duchemin, Anna T. Wachnowicz, Sabrina Hogan, Manina M. Etter, Julia Flammer, Chiara Paganetti, Tomás A. Martins, Philip Schmassmann, Steven Zanganeh, Francois Le Goff, Manuele G. Muraro, Marie-Françoise Ritz, Darci Phillips, Salil S. Bhate, Graham L. Barlow, Garry P. Nolan, Christian M. Schürch#, Gregor Hutter#

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02/2022

CELL SYSTEMS

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01/2022

BMC BIOINFORMATICS

CellSeg: a robust, pre-trained nucleus segmentation and pixel quantification software for highly multiplexed fluorescence images

Michael Y. Lee, Jacob S. Bedia, Salil S. Bhate, Graham L. Barlow, Darci J. Phillips, Wendy J. Fantl, Garry P. Nolan, Christian M. Schürch

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01/2022

RESPIRATION

Systematic investigation of SARS-CoV-2 receptor protein distribution along viral entry routes in humans

Konstantin Bräutigam, Stefan Reinhard, José A. Galván, Martin Wartenberg, Ekkehard Hewer, Christian M. Schürch

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12/2021

FRONT IMMUNOL

Rhesus macaque CODEX multiplexed immunohistochemistry panel for studying immune responses during Ebola infection

Sizun Jiang, Nilanjan Mukherjee, Richard S. Bennett, Han Chen, James Logue, Bonnie Dighero-Kemp, Jonathan R. Kurtz, Ricky Adams, Darci Phillips, Christian M. Schürch, Yury Goltsev, John Hickey, Erin Francis McCaffrey, Alea Delmastro, Pauline Chu, Rachel Reader, Rebekah I. Keesler, Jose A. Galván, Inti Zlobec, Koen K. A. Van Rompay, David X. Liu, Lisa E. Hensley, Garry P. Nolan, David R. McIlwain

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11/2021

CANCERS

Diagnostic and prognostic implications of Caspase-1 and PD-L1 co-expression patterns in Myelodysplastic Syndromes

Johannes Graf, Stefan Forster, Frido Bruehl, Yara Banz, Mahmoud Hallal, Justine Brodard, Vera Ulrike Bacher, Ramanjaneyulu Allam, Christian M. Schürch, Nicolas Bonadies

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11/2021

CELL HOST & MICROBE

Human influenza virus challenge identifies cellular correlates of protection for oral vaccination

David R. McIlwain, Han Chen, Zainab Rahil, Neda Hajiakhoond Bidoki, Sizun Jiang, Zach Bjornson, Nikita S. Kolhatkar, C. Josefina Martinez, Brice Gaudillière, Julien Hedou, Nilanjan Mukherjee, Christian M. Schürch, Angelica Trejo, Melton Affrime, Bonnie Bock, Kenneth Kim, David Liebowitz, Nima Aghaeepour, Sean N. Tucker, Garry P. Nolan

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11/2021

CANCER IMMUNOLOGY RESEARCH

Supporting the next generation of scientists to lead cancer immunology research

Elise Alspach*, Ryan D. Chow*, Shadmehr Demehri*, Jennifer Guerriero*, Shashi Gujar*, Nir Hacohen*, Felix Hartmann*, Beth Helmink*, William H. Hudson*, Won Jin Ho*, Leyuan Ma*, Barbara Maier*, Vivien Maltez*, Brian Miller*, Noor Momin*, Amy Moran* Erin Parry*, Padmini S. Pillai*, Sarwish Rafiq*, Miguel Reina Campos*, Pam Rosato*, Nils-Petter Rudqvist*, Megan K. Ruhland*, Idit Sagiv-Barfi*, Avinash Sahu*, Robert Samstein*, Christian M. Schürch*, Debattama R. Sen*, Daniela Thommen*, Yochai Wolf*, Roberta Zappasodi*

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11/2021

CANCERS

Molecular progression of myeloproliferative and myelodysplastic/myeloproliferative neoplasms: A study on sequential bone marrow biopsies

Magdalena M. Brune, Achim Rau, Mathis Overkamp, Tim Flaadt, Christian M. Schürch, Birgit Federmann, Stefan Dirnhofer, Falko Fend, Alexandar Tzankov

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11/2021

NATURE COMMUNICATIONS

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch#, Garry P. Nolan#

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10 / 2021

CELL REPORTS MEDICINE

Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers

Tsuguhisa Nakayama, Ivan T. Lee, Sizun Jiang, Matthias S. Matter, Carol H. Yan, Jonathan B. Overdevest, Yury Goltsev, Liang-Chun Shih, Chun-Kang Liao, Chien-Ting Wu , Bokai Zhu, David Zarabanda, Angela Yang, Christian M. Schürch, Pauline Chu, Han Chen, David R. McIlwain, Nicole A. Borchard, Phil A. Gall, Sachi S. Dholakia, Le Xu, Anna K. Stalder, Peter Lidsky, Peter K. Jackson, Chih-Jaan Tai, Te-Huei Yeh, Raul Andino, Jason M. Duran, Kirsten D. Mertz , Zara M. Patel, Jasmin D. Haslbauer, Thomas Menter, Peter D. Canoll, Adam S. DeConde, Peter H. Hwang, Alexandar Tzankov, Garry P. Nolan, Jayakar V. Nayak

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10/2021

DER RADIOLOGE

Mutiple myeloma from the pathologist's perspective

Antonio Vogelsberg, Christian M. Schürch, Falko Fend

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07/2021

NATURE PROTOCOLS

CODEX multiplexed tissue imaging with DNA-conjugated antibodies

Sarah Black, Darci Phillips, John W. Hickey, Julia Kennedy-Darling, Vishal G. Venkataraaman, Nikolay Samusik, Yury Goltsev, Christian M. Schürch#, Garry P. Nolan#

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07 / 2021

CELL REPORTS MEDICINE

Virtual and Augmented Reality for Biomedical Applications

Mythreye Venkatesan, Harini Mohan, Justin Ryan, Christian M. Schürch, Garry P. Nolan, David H. Frakes, Ahmet F. Coskun

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05 / 2021

FRONT IMMUNOL

Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging

Darci Phillips, Christian M. Schürch, Michael S. Khodadoust, Youn H. Kim, Garry Nolan and Sizun Jiang

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04 / 2021

FRONT PHARMACOL

Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer

Paulius Ruzgys, Stephan Böhringer, Ayse Sila Dokumaci, Yvonne Hari, Christian M. Schürch, Frido Brühl, Stefan Schürch, Sönke Szidat, Carsten Riether, Saulius Šatkauskas, Thomas Geiser, David Hradetzky, Amiq Gazdhar

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03 / 2021

EUR J IMMUNOL

Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction

Julia Kennedy-Darling, Salil S. Bhate, John W. Hickey, Sarah Black, Graham L. Barlow, Gustavo Vazquez, Vishal G. Venkataraaman, Nikolay Samusik, Yury Goltsev, Christian M. Schürch#, Garry P. Nolan#

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03 / 2021

BLOOD

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02 / 2021

NAT COMMUN

Nanoscopic subcellular imaging enabled by ion beam tomography

Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan

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01 / 2021

CELL REPORTS

Metoclopramide treatment blocks CD93-signaling mediated self-renewal of chronic myeloid leukemia stem cells

Carsten Riether, Ramin Radpour, Nils M. Kallen, Damian T. Bürgin, Chantal Bachmann, Christian M. Schürch, Ursina Lüthi, Miroslav Arambasic, Sven Hoppe, Christoph E. Albers, Gabriela M. Baerlocher, Adrian F. Ochsenbein

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12 / 2020

SCIENCE

Inhibition of prostaglandin degrading enzyme 15-PGDH restores muscle strength in aged mice

Adelaida R. Palla, Meenakshi Ravichandran, Yu Xin Wang, Ludmila Alexandrova, Ann V. Yang, Peggy Kraft, Colin A. Holbrook, Christian M. Schürch, Andrew T. V. Ho, Helen M. Blau

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10 / 2020

NAT COMMUN

ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs

Ivan T. Lee, Tsuguhisa Nakayama, Chien-Ting Wu, Yury Goltsev, Sizun Jiang, Phillip A. Gall, Chun-Kang Liao, Liang-Chun Shih, Christian M. Schürch, David R. McIlwain, Pauline Chu, Nicole A. Borchard, David Zarabanda, Sachi S. Dholakia, Angela Yang, Dayoung Kim, Han Chen, Tomoharu Kanie, Chia-Der Lin, Ming-Hsui Tsai, Katie M. Phillips, Raymond Kim, Jonathan B. Overdevest, Matthew A. Tyler, Carol H. Yan, Chih-Feng Lin, Yi-Tsen Lin, Da-Tian Bau, Gregory J. Tsay, Zara M. Patel, Yung-An Tsou, Alexandar Tzankov, Matthias S. Matter, Chih-Jaan Tai, Te-Huei Yeh, Peter H. Hwang, Garry P. Nolan, Jayakar V. Nayak, Peter K. Jackson

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10 / 2020

J CLIN INVEST

Landscape of coordinated immune responses to H1N1 challenge in humans

Zainab Rahil, Rebecca Leylek*, Christian M. Schürch*, Han Chen*, Zach Bjornson, Shannon Christensen, Pier Federico Gherardini, Salil S. Bhate, Matthew H. Spitzer, Gabriela K. Fragiadakis, Nilanjan Mukherjee, Nelson Kim, Jennifer Yo, Melton Affrime, Bonnie Bock, Scott Hensley, Juliana Idoyaga, Nima Aghaeepour, Kenneth Kim, Garry P. Nolan, David R. McIlwain

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09 / 2020

RESPIRATORY RESEARCH

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08 / 2020

CELL

Coordinated cellular neighborhoods orchestrate antitumoral immunity at the colorectal cancer invasive front

Christian M. Schürch*#, Salil S. Bhate*, Graham L. Barlow*, Darci J. Phillips*, Luca Noti, Inti Zlobec, Pauline Chu, Sarah Black, Janos Demeter, David R. McIlwain, Nikolay Samusik, Yury Goltsev, Garry P. Nolan#

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07 / 2020

CELL METABOLISM

Memory CD8+ T cells balance pro- and anti-inflammatory activity by reprogramming cellular acetate handling at sites of infection

Maria L. Balmer, Raja Epple, Eric H. Ma, Adrian Egli, Lukas Bubendorf, Katharina Rentsch, Anne-Kathrin Woischnig, Nina Khanna, Jonas Lötscher, Philippe Dehio, Gaëlle Perrin, Jan Warncke, Olivier P. Schären, Christian M. Schürch, Gunhild Unterstab, Andrew Thompson, Siegfried Hapfelmeier, Russell G. Jones, Christoph Hess

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06 / 2020

J NUCLEAR MEDICINE

PET imaging of the natural killer cell activation receptor NKp30

Travis M. Shaffer, Amin Aalipour, Christian M. Schürch, Sanjiv S. Gambhir

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04 / 2020

FRONT IMMUNOL

Bispecific Antibodies for Multiple Myeloma: A Review of Targets, Drugs, Clinical Trials, and Future Directions

Chiara Caraccio , Sachi Krishna, Darci J. Phillips and Christian M. Schürch

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04 / 2020

NAT COMMUN

Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity

Simona Pfister, Olivier P. Schären, Miguelangel Cuenca, Stefanie Hagemann, Stefanie S. Uster, Miguel A. Terrazos, Christian M. Schürch, Fernanda M. Coelho, Emma Slack, Maria L. Balmer, Siegfried Hapfelmeier

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04 / 2020

NAT COMMUN

TNIK signaling imprints CD8+ T cell memory formation early after priming

Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Ursina Lüthi, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein

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03 / 2020

BMC IMMUNOLOGY

Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes

Han Chen, Christian M. Schürch, Kevin Noble, Kenneth Kim, Peter Krutzik, Erika O’Donnell, Jason Vander Tuig, Garry P. Nolan, David R. McIlwain

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12/2019

VIRCHOWS ARCHIV

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11/2019

PATHOL RES PRACT

Lobular neoplasia and invasive lobular breast cancer: Inter-observer agreement for histological grading and subclassification

Nora Schaumann, Mieke Raap, Laura Hinze, Luisa Rieger, Christian M. Schürch, Wiebke Antonopoulos, Stefanie Avril, Till Krech, Maximilian Dämmrich, Gian Kayser, Florian Puls, Florian Länger, Marianne Tinguely, Hans Kreipe, Matthias Christgen

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10/2019

NATURE

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07/2019

THYROID

Targeting CD47 in anaplastic thyroid carcinoma enhances tumor phagocytosis by macrophages and is a promising therapeutic strategy

Christian M. Schürch#, Matthias A. Roelli, Stefan Forster, Marie-Hélène Wasmer, Frido Brühl, Renaud S. Maire, Sergio Di Pancrazio, Marc-David Ruepp, Roland Giger, Anja M. Schmitt, Philippe Krebs, Roch-Philippe Charles, Matthias S. Dettmer#

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05 / 2019

CELL

A multiscale map of the stem cell state in pancreatic adenocarcinoma

Nikki K. Lytle, L. Paige Ferguson, Nirakar Rajbhandari, Kathryn Gilroy, Raymond G. Fox, Anagha Deshpande, Christian M. Schürch, Michael Hamilton, Neil Robertson, Wei Lin, Pawan Noel, Martin Wartenberg, Inti Zlobec, Micha Eichmann, José A. Galván, Eva Karamitopoulou, Tami Gilderman, Lourdes Adriana Esparza, Yutaka Shima, Philipp Spahn, Randall French, Nathan E. Lewis, Kathleen M. Fisch, Roman Sasik, Sara Brin Rosenthal, Marcie Kritzik, Daniel Von Hoff, Haiyong Han, Trey Ideker, Aniruddha L. Deshpande, Andrew M. Lowy, Peter D. Adams, Tannishtha Reya

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05/2019

GENES & IMMUNITY

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05 / 2018

FRONT ONCOL

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09 / 2017

ONCOIMMUNOLOGY

The “don’t eat me” signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma

Christian M. Schürch#, Stefan Forster, Frido Brühl, Sara H. Yang, Emanuela Felley-Bosco, Ekkehard Hewer#

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07 / 2017

PATHOBIOLOGY

Tumor heterogeneity in lymphomas – a different breed

Christian M. Schürch, Birgit Federmann, Leticia Quintanilla-Martinez, Falko Fend

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06 / 2017

PLOS PATHOGENS

Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity

Stefanie Buschor, Miguelangel Cuenca, Stephanie S. Uster, Olivier P. Schären, Maria L. Balmer, Miguel A. Terrazos, Christian M. Schürch, Siegfried Hapfelmeier

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05 / 2017

MOL CANCER THER

The multi-kinase inhibitor Debio 0617B reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells

Maximilien Murone, Ramin Radpour, Antoine Attinger, Anne Vaslin Chessex, Anne-Laure Huguenin, Christian M. Schürch, Yara Banz, Saumitra Sengupta, Michel Aguet, Stefania Rigotti, Yogeshwar Bachhav, Frederic Massiere, Murali Ramachandra, Andres McAllister, Carsten Riether

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02 / 2017

J EXP MED

CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia

Carsten Riether*, Christian M. Schürch*, Elias D. Bührer, Magdalena Hinterbrandner, Anne-Laure Huguenin, Sabine Hoepner, Inti Zlobec, Thomas Pabst, Ramin Radpour, Adrian F. Ochsenbein

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12 / 2016

FRONT CELL INFECT MICROBIOL

Functional intestinal bile acid 7-alpha-dehydroxylation by Clostridium scindens associated with protection from C. difficile infection in a gnotobiotic mouse model

Nicolas Studer, Lyne Desharnias, Markus Beutler, Sandrine Brugiroux, Miguel Terrazos, Laure Menin, Christian M. Schürch, Kathy D. McCoy, Sarah Kuehne, Nigel Minton, Bärbel Stecher, Rizlan Bernier-Latmani, Siegfried Hapfelmeier

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07 / 2015

SCIENCE TRANSL MED

Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt-signaling

Carsten Riether*, Christian M. Schürch*, Christoph Flury, Magdalena Hinterbrandner, Linda Drück, Anne-Laure Huguenin, Gabriela M. Baerlocher, Ramin Radpour, Adrian F. Ochsenbein

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07 / 2015

J CLIN INVEST

IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms

Lukas Mager, Carsten Riether*, Christian M. Schürch*, Yara Banz*, Marie-Hélène Wasmer, Regula Stuber, Alexandre P. Theocharides, Xiaohong Li, Yu Xia, Hirohisa Saito, Susumu Nakae, Gabriela M. Baerlocher, Kathy D. McCoy, Andrew J. Macpherson, Adrian F. Ochsenbein, Bruce Beutler, Philippe Krebs

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07 / 2015

CELL DEATH DIFFER

Regulation of hematopoietic and leukemic stem cells by the immune system

Carsten Riether*, Christian M. Schürch*, Adrian F. Ochsenbein

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04 / 2015

LEUK RES

CD47 protein expression in acute myeloid leukemia: a tissue microarray-based analysis

Serena Galli, Inti Zlobec, Christian Schürch, Aurel Perren, Adrian Ochsenbein, Yara Banz

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03 / 2015

LEUKEMIA

Blocking programmed cell death 1 in combination with adoptive cytotoxic T cell transfer eradicates chronic myelogenous leukemia stem cells

Carsten Riether, Thomas Gschwend, Anne-Laure Huguenin, Christian M. Schürch, Adrian F. Ochsenbein

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10 / 2014

J IMMUNOL

Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling

Maria Luisa Balmer, Christian M. Schürch, Yasuyuki Saito, Markus B. Geuking, Hai Li, Miguelangel Cuenca, Larisa V. Kovtonyuk, Kathy D. McCoy, Siegfried Hapfelmeier, Adrian F. Ochsenbein, Markus G. Manz, Emma Slack, Andrew J. Macpherson

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04 / 2014

CELL STEM CELL

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01 / 2014

PLOS PATHOGENS

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

Benjamin Weber, Steffen Schuster, Daniel Zysset, Silvia Rihs, Nina Dickgreber, Christian Schürch, Carsten Riether, Mark Siegrist, Christoph Schneider, Helga Pawelski, Ursina Gurzeler, Pascal Ziltener, Vera Genitsch, Fabienne Tacchini-Cottier, Adrian Ochsenbein, Willy Hofstetter, Manfred Kopf, Thomas Kaufmann, Anette Oxenius, Walter Reith, Leslie Saurer, Christoph Mueller

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12 / 2013

FRONT IMMUNOL

Dendritic cell-based immunotherapy for myeloid leukemias

Christian M. Schürch*, Carsten Riether*, Adrian F. Ochsenbein

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04 / 2013

ONCOIMMUNOLOGY

Interferons in hematopoiesis and leukemia

Christian M. Schürch*, Carsten Riether*, Adrian F. Ochsenbein*

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03 / 2013

PATHOL RES PRACT

Leiomyomatoid angiomatous neuroendocrine tumor (LANT) of the pituitary reflects idiosyncratic angiogenesis in adenomas of the gonadotroph cell lineage

Christian Schürch, Michèle Birrer, Isabelle Estella, Andreas Kappeler, Ekkehard Hewer, Istvan Vajtai

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02 / 2013

J EXP MED

Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ

Christian M. Schürch*, Carsten Riether*, Michael A. Amrein, Adrian F. Ochsenbein

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01 / 2013

SWISS MED WKLY

From “magic bullets” to specific cancer immunotherapy

Carsten Riether*, Christian Schürch*, Adrian F. Ochsenbein*

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12 / 2012

ONCOIMMUNOLOGY

Modulating CD27 signaling to treat cancer

Carsten Riether*, Christian Schürch*, Adrian F. Ochsenbein*

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07 / 2012

CANCER RES

CD27-signaling increases the frequency of regulatory T cells and promotes tumor growth

Christina Claus*, Carsten Riether*, Christian Schürch*, Matthias S. Matter, Tamara Hilmenyuk, Adrian F. Ochsenbein

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02 / 2012

J CLIN INVEST

CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression

Christian Schürch*, Carsten Riether*, Matthias S. Matter, Alexandar Tzankov, Adrian F. Ochsenbein

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09 / 2011

PLOS ONE

Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells

Matthias S. Matter, Tamara Hilmenyuk, Christina Claus, Romina Marone, Christian Schürch, Marianne Tinguely, Luigi Terracciano, Sanjiv A. Luther, Adrian F. Ochsenbein

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07 / 2010

EUR J IMMUNOL

Chronic myelogenous leukemia maintains leukemia-specific CD8+ T cells through IL-7 signaling

Sabine Mumprecht*, Christian Schürch*, Sandro Scherrer, Christina Claus, Adrian F. Ochsenbein

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08 / 2009

BLOOD

Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T cell exhaustion and disease progression

Sabine Mumprecht, Christian Schürch, Jürg Schwaller, Max Solenthaler, Adrian F. Ochsenbein

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05 / 2009

BLOOD

Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells

Sabine Mumprecht, Christina Claus, Christian Schürch, Viktor Pavelic, Matthias S. Matter, Adrian F. Ochsenbein

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03 / 2007

ANTIMICROB AGENTS CHEMOTHER

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