PUBLICATIONS

Click here for a list of all publications

pre-print

BIORXIV

High-Dimensional Spatiotemporal Single-Cell and 3D Atlas of the Bone Marrow Microenvironment during Leukemic Progression

Lanzhu Li, Geoff Ivison, Isabelle Rottmann, Jan C. Schröder, Yury Goltsev, Garry P. Nolan, Aaron T. Mayer, Borhan R. Saeed, Bettina Weigelin, Christian M. Schürch

10/2025

LABORATORY INVESTIGATION

A validation workflow for novel oligonucleotide sequences to expand the multiplexing capacity of the CO-Detection by indEXing (CODEX) platform

Alexander Rochwarger, Louisa Kaufmann, Jing Zhao, Ahmad Makky, Nhat Anh Nguyen, Nastassja Lehmann, Nikolay Samusik, Christine Beschorner, Saumya S. Manmadhan, Karen Greif, Christian M. Schürch

10/2025

COMPUTERS IN BIOLOGY AND MEDICINE

Studying Therapy Effects and Disease Outcomes in Silico using Artificial Counterfactual Tissue Samples

Martin Paulikat, Christian M. Schürch#, Christian F. Baumgartner#

01/2023

SCIENCE ADVANCES

A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy

Aaron T. Mayer*, Derek R. Holman*, Anav Sood*, Utkarsh Tandon, Salil S. Bhate, Sunil Bodapathi, Graham L. Barlow, Jeff Chang, Sarah Black, Erica C. Crenshaw, Alexander N. Koron, Sarah E. Streett, Sanjiv S. Gambhir, William J. Sandborn, Brigid S. Boland, Trevor Hastie, Robert Tibshirani, John T. Chang, Garry P. Nolan, Christian M. Schürch#, Stephan Rogalla#

07/2022

SCIENCE ADVANCES

Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery

Tala Shekarian, Carl P. Zinner, Ewelina M. Bartoszek, Wandrille Duchemin, Anna T. Wachnowicz, Sabrina Hogan, Manina M. Etter, Julia Flammer, Chiara Paganetti, Tomás A. Martins, Philip Schmassmann, Steven Zanganeh, Francois Le Goff, Manuele G. Muraro, Marie-Françoise Ritz, Darci Phillips, Salil S. Bhate, Graham L. Barlow, Garry P. Nolan, Christian M. Schürch#, Gregor Hutter#

01/2022

BMC BIOINFORMATICS

CellSeg: a robust, pre-trained nucleus segmentation and pixel quantification software for highly multiplexed fluorescence images

Michael Y. Lee, Jacob S. Bedia, Salil S. Bhate, Graham L. Barlow, Darci J. Phillips, Wendy J. Fantl, Garry P. Nolan, Christian M. Schürch

11/2021

NATURE COMMUNICATIONS

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch#, Garry P. Nolan#

07/2021

NATURE PROTOCOLS

CODEX multiplexed tissue imaging with DNA-conjugated antibodies

Sarah Black, Darci Phillips, John W. Hickey, Julia Kennedy-Darling, Vishal G. Venkataraaman, Nikolay Samusik, Yury Goltsev, Christian M. Schürch#, Garry P. Nolan#

03 / 2021

BLOOD

Diversity, localization and (patho)physiology of mature lymphocyte populations in the bone marrow

Christian M. Schürch, Chiara Caraccio, Martijn A Nolte

08 / 2020

CELL

Coordinated cellular neighborhoods orchestrate antitumoral immunity at the colorectal cancer invasive front

Christian M. Schürch*#, Salil S. Bhate*, Graham L. Barlow*, Darci J. Phillips*, Luca Noti, Inti Zlobec, Pauline Chu, Sarah Black, Janos Demeter, David R. McIlwain, Nikolay Samusik, Yury Goltsev, Garry P. Nolan#